JAMIA HAMDARD

• Dr Sayeed Ahmad, Pharmacognosy & Phytochemistry, SPER, HoD, Food Tech, SIST, JH, (Director CoE in Unani Medicine) (Coordinator & PI).
• Dr Asim ali Khan, Dean, SUMER, JH (PI).
• Dr Anwar Hussain, HOD, Physiology, SUMER, JH (Co-PI).
• Dr Mohammad Ahmed Khan, Pharmacology, SPER, JH (Co-PI).
• Dr S M Arif Zaidi, SUMER, JH.
• Dr Hifzul Kabir, SUMER, JH.

• To develop a state of the art facility for Quality control and Scientific validation of traditional claims of Unani medicines using modern scientific tools.
• To develop patentable AYUSH based formulations using synergy based approach and re-design of traditional Unani sugar based formulations into sugar free dosage forms.
• To undertake stability testing, pharmacokinetic analysis, metabolomic profiling, network pharmacology based research and clinical evaluation of Unani medicines.
• To carry out training and competency development of Unani/AYUSH professionals in the area of advanced research and innovation in the field of Unani medicine.
• To publish, generate IPR and create a web based open source repository of scientific data as per the global standards.

Construction and renovation work including Furniture work

First Year

• Development of Extraction / Sample Preparation Unit.    Completed
• Development of Cell Culture and Molecular Pharmacology Facility.    Work in progress
• Development of NABL Accredited Advanced Testing Laboratory for AYUSH Medicine.    Work in progress
• Development of Seminar hall and Conference room.    Completed

Second Year

• Development of In vivo Experiment Unit.    Work in progress
• Development of Formulation Development Unit.    Completed

Purchase of Modern Analytical Equipment’s

Second Year

• Purchase of HPTLC, HPLC & LCMS, Multi-Mode Reader, Inverted Microscope, Incubator, Minus eighty and other cell culture accessories.

Third Year

• Purchase of ICP-MS and accessories.

Development of patentable AYUSH based formulations using synergy based approach for management of chronic kidney disease (CKD)

First Year

• Selection of best active extracts (aqueous / hydroalcoholic) of Unani medicinal plants used in different formulations for kidney disorders on the basis of in vitro activity .    Completed

Second Year

• Development of synergy based combinations of best active extracts using isobolographic model.    Completed

Third Year

• Evaluation of in-vivo biological activity and toxicity testing of the synergistic combination.

Redesign of traditional Unani sugar based formulations into sugar free dosage forms as per the mandate of CCRUM

First Year

• Development of sugar free formulations of two best active sugar based formulations used for kidney disorders.    Completed

Second Year

• Comparative quality control and pharmacological evaluation of traditional and sugar free formulation for CKD.    Completed

Second Year

• To perform stability testing and shelf life studies on Unani formulations.    Completed
• To perform LCMS and GCMS based metabolomic studies for identification of total metabolites present in the formulation.    Work in progress

Third Year

• To carry out Pharmacokinetic evaluation of Unani formulations.
• To perform clinical studies on the AYUSH formulations as developed/ selected in above experiments (Two sugar free and one synergy based combination formulations).

First Year

• To organise 3 professional hands on training and workshops, one national / international Seminar.    Completed

Second Year

• To organise 3 professional hands on training and workshops, one national / international Seminar.

Third Year

• To organise 4 professional hands on training and workshops, one international Conference.
• To provide opportunity to AYUSH professionals for research training and testing facility.

First Year

• 5 publications in good impact factor Journal + 2 Monographs of medicinal plants.    Completed

Second Year

• 7 publications in good impact factor Journal + 3 Monographs of medicinal plants

Third Year

• 8 publications in good impact factor Journal + 5 Monographs/ SOPs of formulations / Medicinal plants including developed formulations.
• To generate at least 02 patents from the research work.
• To create an exclusive web portal for open data sharing with academic and research institutions as per global standards.